An original method is reported for synthesis of bioactive glass 45S5 Bioglass and related glass- ceramics doped with 5, 15, 25, and 60 wt % of boron through pyrolysis of a mixture of organic precursors— tetraethoxysilane, tributyl phosphate, sodium oleate, and calcium oleate—in a liquid phase. A high boron content (>25 wt %) has been achieved by substitution of B2O3 for a part of SiO2 in the samples through the use of a highly concentrated organic solution of boron obtained by liquid-solid phase extraction. The com- position and physicochemical characteristics of the obtained biosamples have been studied by IR spectros- copy, 31Р, 11В, and 29Si NMR, XRD, SEM, and EDX. The antibacterial properties of bioglasses have been assessed during the formation of biofilms of conditionally pathogenic bacteria Pseudomonas aeruginosa on their surface with different morphologies depending on the boron concentration in the samples. The prospect of this method is that it can afford biocompatible boron-containing glasses as bulk materials, as well as thin- layer coatings on the surface and in the intraporous volume of inert ceramics, which can be crucial for solving problems of bone implantology in modern medicine.

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